Circadian changes in the QT variability index in the beagle dog.

Seasonal and circadian variations of hemodynamic and electrocardiographic parameters in telemetered beagle dogs

QT PRODACT: in vivo QT assay in the conscious dog for assessing the potential for QT interval prolongation by human pharmaceuticals.

The goal of the present study was to examine the utility of the conscious dog model by assessing the QT-interval-prolonging potential of ten positive compounds that have been reported to induce QT interval prolongation in clinical use and seven negative compounds considered not to have such an effect. Three doses of test compounds or vehicle were administered orally to male beagle dogs (n=4), a...

Microsatellite loci analysis for the genetic variability and paternal lineages in Iranian native dogs

Genetic variation among the individuals is considered as an important tool for conservation of livestock animals. This study was conducted to analyze the genetic variation, phylogenetic relationship and paternal lineages among Iranian dog populations using seventeen autosomal and Y chromosome-specific microsatellite markers. Total DNAs of the samples were extracted and applied for genotype anal...

Changes in QT interval before and after hemodialysis

Background: Cardiovascular mortality and morbidity are high in chronic renal failure (CRF) patients. Increased dispersion of QT intervals is known to predispose to ventricular arrhythmias and sudden cardiac death. This study was conducted to assess the effect of hemodialysis (HD) on corrected QT (QTc) intervals and their dispersions (QTd) in chronic hemodialyzed patients. Methods: Fifty-eight p...

همسانی درونی و تحلیل عامل تائیدی نسخه فارسی پرسشنامه نوع سیرکادین (CTI)در شاغلین روزکار و نوبتکار ایرانی_ سال1390

  Background and aims : "circadian" is the changes of behavioral and metabolic activity during day and night in living organisms. The human body has circadian rhythm too, which is repeated every 24 hours. The aim of this study is to determine the validity and reliability of the 11Q of CTI questionnaire, according to Iranian workers society.   Methods : Translation and cultural adaptation of CTI...